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Amebic Liver Abscess in Rat: Morphological Evidence of Innate Immune Modulation by the Sympathetic Nervous System International Journal of Morphology
Muñoz-Ortega,Martín Humberto; Cervantes-García,Daniel; Quintanar-Stephano,Andrés; Campos-Esparza,María del Rosario; García-Lorenzana,Mario; Campos-Rodríguez,R; Rodríguez,M. G; Ventura-Juárez,Javier.
All organs of the immune system are innervated and almost all neurotransmitter receptors are present on immune cells. We studied the effects of sympathetic innervation in the development of amebic liver abscess (ALA) in rats. Our results showed that lack of sympathetic innervation promote a decrease in size of ALA. We found scarce amoebas, increased the number of neutrophils and a few collagen fibers surrounding the abscess, meanwhile in control group, we observed abscesses areas with typical necrosis including trophozoites and neutrophils. Macrophages were differentially distributed surrounding abscess area in control and vehicle groups, but equally located in and outside of the abscesses in sympathectomized rat. No significant differences were observed...
Tipo: Journal article Palavras-chave: Sympathectomy; Rat; E. histolytica; Amebic liver abscess.
Ano: 2015 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000100034
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Ultrastructural analysis and identification of membrane proteins in the free-living amoeba Difflugia corona Biocell
Silva-Briano,Marcelo; Martínez-Hernández,Sandra Luz; Adabache-Ortíz,Araceli; Ventura-Juárez,Javier; Salinas,Eva; Quintanar,J. Luis.
Syntaxin-1 and 25-kDa Synaptosome-associated Protein (SNAP-25) are present in the plasma membrane of several different secretory cell types and are involved in the exocytosis process. In this work, the free-living amoeba Difflugia corona was studied in relation to ultrastructure, structural membrane proteins, and proteins such as Syntaxin-1 and SNAP-25. Our results obtained by scanning electron microscopy in the amoeba without its theca, showed many membrane projections and several pore-like structures. Using immunocytochemistry, we found structural proteins Syntaxin-1 and SNAP-25.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Amoeba; Membrane proteins; Pore-like; Theca; Ultrastructure.
Ano: 2007 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452007000200004
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